Software
TFCat: the curated catalog of mouse and human transcription factors
- † Equal contributors
1 Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics - Child and Family Research Institute, University of British Columbia, West 28th Avenue, Vancouver, V5Z 4H4, Canada
2 Departments of Medicine and Human Genetics, McGill University and Genome Quebec Innovation Centre, Dr. Penfield Avenue, Montreal, H3A 1A4, Canada
3 Banting and Best Department of Medical Research, University of Toronto, College Street, Toronto, M5S 3E1, Canada
4 Center for Developmental Therapeutics, Seattle Children's Research Institute, Olive Way, Seattle, 98101, USA
Genome Biology 2009, 10:R29 doi:10.1186/gb-2009-10-3-r29
Published: 12 March 2009Abstract
Unravelling regulatory programs governed by transcription factors (TFs) is fundamental to understanding biological systems. TFCat is a catalog of mouse and human TFs based on a reliable core collection of annotations obtained by expert review of the scientific literature. The collection, including proven and homology-based candidate TFs, is annotated within a function-based taxonomy and DNA-binding proteins are organized within a classification system. All data and user-feedback mechanisms are available at the TFCat portal http://www.tfcat.ca webcite.
