Table 3

Highly divergent milk proteins

Protein name

GLEAN ID*

Gene symbol

Average PID

Alpha-S1-casein

GLEAN_22124_P02662

CSN1S1

44.4

G protein Xlalphas

GLEAN_10239

GNAS

48.6

Kappa casein

GLEAN_22128

CSN3

51.3

Mucin 1

GLEAN_00552

MUC1

52.2

Beta casein

GLEAN_22133

CSN2

55.4

Rab 10

GLEAN_18819_A6QLS9

RAB10

57.6

SCAMP2

GLEAN_09359_A6QR35

SCAMP2

63.6

Fetuin

GLEAN_07528

AHSG

64.5

Immunoglobulin IgM

GLEAN_18189

IgM

65.0

Polymeric-immunoglobulin receptor precursor

GLEAN_25657

PIGR

66.7

Keratin 9

GLEAN_21315

KRT9

66.9

CD14

GLEAN_04279

CD14

68.0

Rab 7

GLEAN_25742

RAB7A

68.3

Peptidoglycan recognition protein

GLEAN_12036

PGLYRP1

68.5

Fibrinogen alpha chain

GLEAN_24372

FGA

68.6

Apolipoprotein B

GLEAN_00959

APOB

69.4

Apolipoprotein E

GLEAN_10715

APOE

70.0

Glycoprotein antigen MGP57/53 (lactadherin/bP47 protein)

GLEAN_17418

MFGE8

70.3

Toll-like receptor 4

GLEAN_05263

TLR4

70.7

Alpha-lactalbumin

GLEAN_17221

LALBA

70.7

MUC15 protein

GLEAN_04480

MUC15

71.0

Macrophage scavenger receptor types I and II

GLEAN_13926

MSR1

72.1

Toll-like receptor 2

GLEAN_24366

TLR2

73.1

Albumin (precursor)

GLEAN_11814

ALB

74.6

Chitinase-like protein 1 (CLP-1)

GLEAN_07846

CHI3L1

76.3

*Manually curated full length sequences are indicated by the following accession format: GLEAN_ID_ACCESSION where ACCESSION is the UniProt accession for the replacement amino acid sequence and GLEAN_ID is the bovine consensus gene identifier for the original sequence.

Lemay et al. Genome Biology 2009 10:R43   doi:10.1186/gb-2009-10-4-r43