Figure 1.

Empirical distribution function of number of pathways associated with genes at given distances from terminal nodes. Empirical cumulative distribution function of the number of pathways that are associated with genes that have gene products located at a given distance, d (= 0, 1, 2, 3, 4), from a terminal node of the pathway network. Gene products that are at a distance d = 0 are the terminal gene products. The data used were those of all the genes associated with human signaling pathways in the KEGG pathway database [44].