Genome Biology

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Co-evolutionary networks of genes and cellular processes across fungal species

Tamir Tuller1,2,3*, Martin Kupiec2* and Eytan Ruppin1,3

Author Affiliations

1 School of Computer Sciences, Tel Aviv University, Ramat Aviv 69978, Israel

2 Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Ramat Aviv 69978, Israel

3 School of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel

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Genome Biology 2009, 10:R48 doi:10.1186/gb-2009-10-5-r48

Published: 5 May 2009

Additional files

Additional file 1:

Orthologous sets that exhibit positive evolution for each of the tree branches.

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Additional file 2:

Supplementary notes 1 to 6.

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Additional file 3:

GO processes with less than 20 genes (biological process ontology) sorted by their mean rERP and variance of rERP.

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Additional file 4:

Mean correlation between the evolutionary patterns of pairs of GO groups (y-axis) as a function of their distance (the shortest connecting pathway) in the GO network (x-axis) when using the ontology of S. pombe.

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Additional file 5:

Pairs of GO groups exhibiting a significant correlation between their rERPs.

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Additional file 6:

GO enrichments (biological process) for the conserved and non-conserved genes.

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Additional file 7:

Distribution of the number of annotations per gene for the conserved and non-conserved genes.

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Additional file 8:

ER values computed in our study versus the ER values computed in Wall et al. [8].

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