Location and density of unique SNPs in TgCkUg2. The graph shows the number of SNPs per 100 kb, where TgCkUg2 had a different allele compared with Me49 and VEG. New SNPs were distributed across the whole genome, but very high densities were found near the telomeres of chromosomes III, VIIa, IX and X, but also in central regions of chromosomes VI and VIII. These mutation hot-spots were mostly located in intergenic regions, but also caused a high number of mutations in the genes for hypothetical proteins 2.m00067, 42.m07434 and the rhoptry antigen ROP5 (551.m00238).
Bontell et al. Genome Biology 2009 10:R53 doi:10.1186/gb-2009-10-5-r53