The Cell Cycle Ontology: an application ontology for the representation and integrated analysis of the cell cycle process

doi:10.1186/gb-2009-10-5-r58

Genome Biology

Volume 10
Issue 5

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Antezana E
Egaña M
Blondé W
Illarramendi A
Bilbao I
De Baets B
Stevens R
Mironov V
Kuiper M

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Antezana E
Egaña M
Blondé W
Illarramendi A
Bilbao I
De Baets B
Stevens R
Mironov V
Kuiper M
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The Cell Cycle Ontology: an application ontology for the representation and integrated analysis of the cell cycle process

Erick Antezana¹^,2 , Mikel Egaña³ , Ward Blondé⁴ , Aitzol Illarramendi⁵ , Iñaki Bilbao⁵ , Bernard De Baets⁴ , Robert Stevens³ , Vladimir Mironov⁶ and Martin Kuiper⁶

¹Department of Plant Systems Biology, VIB, Technologiepark 927, B-9052 Gent, Belgium

²Department of Molecular Genetics, Ghent University, Technologiepark 927, B-9052 Gent, Belgium

³School of Computer Science, University of Manchester, Oxford Road, Manchester M13 9PL, UK

⁴Department of Applied Mathematics, Biometrics and Computer Science, Ghent University, Coupure links 653, B-9000 Gent, Belgium

⁵Noray Bioinformatics, SL Parque Tecnológico 801 A, 2°, 48160 Derio (Bizkaia), Spain

⁶Department of Biology, Norwegian University of Science and Technology, Høgskoleringen 5, NO-7491 Trondheim, Norway

author email corresponding author email

Genome Biology 2009, 10:R58doi:10.1186/gb-2009-10-5-r58


Published:	29 May 2009

Subject areas: Bioinformatics, Cell biology

Abstract

The Cell Cycle Ontology (http://www.CellCycleOntology.org) webcite is an application ontology that automatically captures and integrates detailed knowledge on the cell cycle process. Cell Cycle Ontology is enabled by semantic web technologies, and is accessible via the web for browsing, visualizing, advanced querying, and computational reasoning. Cell Cycle Ontology facilitates a detailed analysis of cell cycle-related molecular network components. Through querying and automated reasoning, it may provide new hypotheses to help steer a systems biology approach to biological network building.