Coverage of gap regions. Sequence coverage of the gap regions on human chromosome 15 is shown for gaps at (a) 24 Mb, (b) 25 Mb and (c) 96 Mb. The x-axis indicates base position in the local region containing each gap. The y-axis shows sequence coverage obtained in 454 reads (red line) and small insert library reads (blue line). Coverage was computed as the average in 10-base non-overlapping windows. Arrows indicate primers used to amplify the amplicons sequenced, color coded in pairs. Bars at top indicate bases present in the Celera (dark gray) and NCBI build 36 (light gray) assemblies.
Garber et al. Genome Biology 2009 10:R60 doi:10.1186/gb-2009-10-6-r60