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Probe-level estimation improves the detection of differential splicing in Affymetrix exon array studies

Essi Laajala, Tero Aittokallio, Riitta Lahesmaa and Laura L Elo*

Genome Biology 2009, 10:R77 doi:10.1186/gb-2009-10-7-r77

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The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer

Maria H Traka, Caroline A Spinks, Joanne F Doleman, Antonietta Melchini, Richard Y Ball, Robert D Mills, Richard F Mithen Molecular Cancer 2010, 9:189 (13 July 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The isothiocyanate sulforaphane found at high levels in broccoli modulates PTEN tumor suppressor gene activity and provides further evidence that dietary components could be of benefit in preventing prostate cancer.

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