Distribution of read depth. (a) Distribution of mapped read depth in all autosomal chromosomes. Read depth is sampled at every position along the chromosomes. The solid line represents a Poisson distribution with the same mean. (b) Distribution of read depth as a function of GC-content. GC-content and read depth were calculated for non-overlapping windows of 500 bp.
Eck et al. Genome Biology 2009 10:R82 doi:10.1186/gb-2009-10-8-r82