Tetranucleotide frequency predicted by codon abundance (a weighted average of the frequencies of the 12 potential codons associated with each tetranucleotide) versus observed tetranucleotide frequency. (a) Color indicates the genome of origin (using the same color scheme as Figure 3). (b) Palindromic nucleotides are indicated in red. R2 indicates the square of the Pearson correlation coefficient.
Dick et al. Genome Biology 2009 10:R85 doi:10.1186/gb-2009-10-8-r85