Additional data file 1.
Figure S1: z-score distribution from the mutual information calculation between all gene-TF pairs. Figure S2: number of regulations in the model depending on the cutoff threshold selection. Figure S3: efficiency (precision, sensitivity and F-score) of the transcriptional model with respect to the reference set. The vertical dashed line indicates the optimum value for the z-score threshold (= 5) according to the F value. Figure S4: gene distribution in the pathways (clusters) found in the transcriptional network. Figure S5: stress distribution of the transcriptional network. Figure S6: absolute and relative gene expression errors versus the regression coefficient between the experimental and predicted gene expressions for all conditions from the training set. Figure S7: regression coefficient between the experimental and predicted gene expressions for all conditions versus the number of TFs regulating that gene. Figure S8: predictive power for gene expression of the effective model (including the transcriptional and non-transcriptional layers). We show the regression coefficient (R2) between the model and experimental profiles across the 1,436 conditions for the best (top) and worst (bottom) predicted genes.
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Carrera et al. Genome Biology 2009 10:R96 doi:10.1186/gb-2009-10-9-r96