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Targeting viral infection by microRNA inhibition

Ashley PE Roberts and Catherine L Jopling*

Author Affiliations

School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK

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Genome Biology 2010, 11:201 doi:10.1186/gb-2010-11-1-201

Published: 26 January 2010

Abstract

An inhibitor of microRNA-122 reduces viral load in chimpanzees that are chronically infected with hepatitis C virus, suggesting that such an approach might have therapeutic potential in humans.