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Open Access Highly Accessed Research

Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome

Jie Zheng1, Pavel P Khil2, R Daniel Camerini-Otero2* and Teresa M Przytycka1*

Author Affiliations

1 Computational Biology Branch, NCBI, NLM, National Institutes of Health, 8600 Rockville Pike, Bethesda, MD 20894, USA

2 Genetics and Biochemistry Branch, NIDDK, National Institutes of Health, 5 Memorial Drive, Bethesda, Maryland 20892, USA

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Genome Biology 2010, 11:R103  doi:10.1186/gb-2010-11-10-r103

Published: 20 October 2010

Additional files

Additional file 1:

A tab-delimited table in which each row is a hotspot-SNP pair in our original dataset, and columns are positions of hotspots and SNPs, rs (reference SNP ID) number of SNPs and LDsplit P-values and q-values.

Format: TXT Size: 5.3MB Download file

Open Data

Additional file 2:

Source code for the LDsplit program and simulation along with a user's manual.

Format: ZIP Size: 679KB Download file

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Additional file 3:

Figures S1 to S4 and Tables S1 to S6.

Format: DOC Size: 401KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data