Profiles of recombination rate at the DNA2 hotspot in the MHC region in chromosome 6 of the three populations (HapMap phase II). For simplicity, we set the position of FG11 SNP at 0. The DNA2 hotspot spans from about -1 kb to 0.5 kb. In each population, the top profile is from the whole sample (T or C allele at FG11); the middle profile is from the subpopulation with the T allele (hot); the bottom profile is from the subpopulation with the C allele (cold). The population and the alleles at FG11 are labeled above each plot.
Zheng et al. Genome Biology 2010 11:R103 doi:10.1186/gb-2010-11-10-r103