Table 2

Average performance of LDsplit on simulation data

Condition

Correct prediction of hot/cold alleles (%)

Sensitivity (%)

Specificity (%)

Positive predictive value (%)


Normal

89.26 ± 18.23

63.15 ± 26.42

58.71 ± 26.53

46.29 ± 22.22

Recurrent mutation

93 ± 9.88

70 ± 27.16

51.78 ± 21.99

43.58 ± 22.49

Long BGC tract (10 kb)

84.29 ± 22.77

53.4 ± 28.34

75.65 ± 12.94

52.60 ± 25.27


The standard deviations are slightly high because we sampled only ten sets of haplotypes for each parameter configuration due to the high computational cost of LDsplit.

Zheng et al. Genome Biology 2010 11:R103   doi:10.1186/gb-2010-11-10-r103

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