Metastasis suppression: a role of the Dice(r)
1 Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
2 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
3 Current address: Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
4 MIT Ludwig Center for Molecular Oncology, Cambridge, MA 02139, USA
Genome Biology 2010, 11:141 doi:10.1186/gb-2010-11-11-141Published: 30 November 2010
Recent studies have implicated the microRNA biogenesis enzyme Dicer as a suppressor of breast carcinoma metastasis and elucidated upstream signaling pathways that control Dicer levels.