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Metastasis suppression: a role of the Dice(r)

Scott Valastyan123 and Robert A Weinberg124*

Author Affiliations

1 Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA

2 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

3 Current address: Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA

4 MIT Ludwig Center for Molecular Oncology, Cambridge, MA 02139, USA

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Genome Biology 2010, 11:141  doi:10.1186/gb-2010-11-11-141

Published: 30 November 2010

Abstract

Recent studies have implicated the microRNA biogenesis enzyme Dicer as a suppressor of breast carcinoma metastasis and elucidated upstream signaling pathways that control Dicer levels.