Table 1

Statistics of exome sequencing and reads mapping

HCC1954

HCC1954BL


Number of 454 reads

6,878,120

6,658,357

Total bases pairs

2,588,213,873

2,325,966,906

Uniquely mapped reads

6,645,304 (97%)

6,385,651 (96%)

Reads uniquely mapped to primary targets

4,806,828 (70%)

4,310,274 (65%)

Target coverage

94.8%

96.0%

Mean target coverage

19.4×

18.1×

Median target coverage

16×

16×

Coverage enrichment by exome sequencing

23×

24×

Total high-confidence (HC) SNVs (known SNVs)

13,102 (12,145)

14,219 (13,309)

HC heterozygous SNVs (known SNVs)

5,602 (4,954)

8,203 (7,408)

HC heterozygous SNVs in CDS (known SNVs)

5,329 (4,709)

7,848 (7,082)


CDS, coding sequence; SNV, single nucleotide variant.

Zhao et al. Genome Biology 2010 11:R114   doi:10.1186/gb-2010-11-11-r114

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