Table 4

Average endocannabinoid levels of FAAH and MGLL rare variant carrier groups at the most significant locus-variants in the three intervals

AEA

2-AG



N

Average (pmol/ml)

SD

P-valuea

N

Average (pmol/ml)

SD

P-valuea


FAAH promoter locus-variant

0.05

0.10

Carrier

Cases

14

17.11

5.79

14

10.55

10.67

Controls

0

NA

NA

0

NA

NA

Non-carrier

Cases

80

15.13

5.34

67

5.63

3.04

Controls

48

13.76

5.51

35

6.98

4.15

MGLL intron 3 locus-variant

0.49

0.80

Carrier

Cases

5

15.6

6.35

4

6.43

2.08

Controls

0

NA

NA

0

NA

NA

Non-carrier

Cases

89

15.24

5.44

77

6.49

5.57

Controls

48

13.76

5.52

35

6.99

4.16

MGLL promoter locus-variant

0.36

0.37

Carrier

Cases

26

15.09

5.6

24

6.31

3.06

Controls

3

13.16

5.38

3

4.41

4.46

Non-carrier

Cases

68

15.56

5.43

57

6.56

6.2

Controls

45

13.8

5.58

32

7.22

4.11


aTwo-tailed t-test P-value between carriers/cases and non-carriers/controls. NA, not available.

Harismendy et al. Genome Biology 2010 11:R118   doi:10.1186/gb-2010-11-11-r118

Open Data