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Creating a blood line from human skin

Michael H Sieweke

Author Affiliations

Centre d'Immunologie de Marseille-Luminy, Université Aix-Marseille, Campus de Luminy, Case 906, 13288 Marseille Cedex 09, France

Institut National de la Santé et de la Recherche Médicale, U631, 13288 Marseille Cedex 09, France

Centre National de la Recherche Scientifique, UMR6102, 13288 Marseille Cedex 09, France

Temporary address: Australian Regenerative Medicine Institute, Monash University, Clayton Campus, Melbourne, VIC 3800, Australia

Genome Biology 2010, 11:143  doi:10.1186/gb-2010-11-12-143

Published: 20 December 2010

Abstract

A recent study has generated blood cell progenitors with therapeutic potential by direct lineage conversion of human fibroblasts, thus circumventing reprogramming to pluripotent stem cells.