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The Genomic HyperBrowser: inferential genomics at the sequence level

Geir K Sandve1, Sveinung Gundersen2, Halfdan Rydbeck135, Ingrid K Glad4, Lars Holden3, Marit Holden3, Knut Liestøl15, Trevor Clancy2, Egil Ferkingstad3, Morten Johansen6, Vegard Nygaard6, Eivind Tøstesen6, Arnoldo Frigessi37 and Eivind Hovig1236*

Author Affiliations

1 Department of Informatics, University of Oslo, Blindern, 0316 Oslo, Norway

2 Department of Tumor Biology, The Norwegian Radium Hospital, Oslo University Hospital, Montebello, 0310 Oslo, Norway

3 Statistics For Innovation, Norwegian Computing Center, 0314 Oslo, Norway

4 Department of Mathematics, University of Oslo, Blindern, 0316 Oslo, Norway

5 Centre for Cancer Biomedicine, The Norwegian Radium Hospital, Oslo University Hospital, Montebello, 0310 Oslo, Norway

6 Institute for Medical Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Montebello, 0310 Oslo, Norway

7 Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Blindern, 0317 Oslo, Norway

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Genome Biology 2010, 11:R121  doi:10.1186/gb-2010-11-12-r121

Published: 23 December 2010

Additional files

Additional file 1:

Supplementary material. Miscellaneous supplementary material: gene coverage example. On the importance of realistic null models. On mathematics of genomic tracks. On system architecture. On Exon DNA melting example. Supplementary figures and tables.

Format: DOC Size: 1.1MB Download file

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Additional file 2:

Statistical tests. Detailed description of the statistical tests implemented in the software system.

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Additional file 3:

Supplementary note on simulation. Description of basic algorithms for simulating synthetic tracks, used to assess statistical tests.

Format: DOC Size: 44KB Download file

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