Table 1

The coverage of gene groups by different sources of functional information

Origin

Age

Number of genes

Pfam coveragea

Fraction essentialb

GO MF coveragec

Fraction with interactionsd


Novel

Old

2696

0.36

0.30

0.67

0.77

Young

239

0.12

0.00

0.22

0.25

Duplicate

Old

1434

0.57

0.30

0.88

0.81

WGD

1087

0.45

0.08

0.76

0.72

Young

314

0.53

0.02

0.60

0.55


aPfam coverage: average fraction of protein length covered by Pfam domains; bfraction essential: fraction of genes in each group that are essential; cGO MF coverage: fraction of genes with Gene Ontology (GO) Molecular Function (MF) annotations; dfraction with interactions: fraction of genes with interactions in the protein physical interaction network. Each statistic is calculated over those genes whose proteins have known physical interactions.

Capra et al. Genome Biology 2010 11:R127   doi:10.1186/gb-2010-11-12-r127

Open Data