Research highlight
PRDM9 points the zinc finger at meiotic recombination hotspots
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Correspondence: Matthew J Neale m.neale@sussex.ac.uk
MRC Genome Damage and Stability Centre, University of Sussex, Brighton BN1 9RQ, UK
Genome Biology 2010, 11:104 doi:10.1186/gb-2010-11-2-104
Published: 26 February 2010Abstract
Meiotic recombination events are spread nonrandomly across eukaryotic genomes in 'hotspots'. Recent work shows that a unique histone methyltransferase, PRDM9, determines their distribution.