Table 3

MicroRNA overexpression motif predictions

mRNA_32 hr

Protein

Seed motif

Score

ERMIT

Score

Seed motif

Score

ERMIT

Score

let-7b

CTACCTc

5.4

GSCCCCS

15.2

CTACCTc

9.1

MTACCTcw

9.7

miR-1

ACATTCc

13.8

RCATTCc

14.5

ACATTCc

8.5

wnRCATTCc

9.9

miR-16

gCTGCTA

7.4

wwgCTGCT

10.2

gCTGCTA

10.3

tgCKGCTR

11.6

miR-155

AGCATTa

12.6

WGCRTTa

13.6

AGCATTa

13.4

GCATTaw

15.2

miR-30a

gTTTACA

10.0

ygTTTACR

10.9

gTTTACA

7.5

wgTTTACAw

8.5

The letters in bold correspond to the canonical 6-mer microRNA seed (that is, the complementary sequence to positions 2 through 7). For each microRNA we report the best of four canonical 6- to 8-mer seed match scores based on the ERMIT objective function, and the corresponding motif prediction resulting from the motif search (data from [44]).

Georgiev et al. Genome Biology 2010 11:R19   doi:10.1186/gb-2010-11-2-r19