Genome Biology

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Identification of functional modules that correlate with phenotypic difference: the influence of network topology

Jui-Hung Hung1, Troy W Whitfield2, Tun-Hsiang Yang1, Zhenjun Hu1,3, Zhiping Weng1,2,3* and Charles DeLisi1,3*

Author Affiliations

1 Bioinformatics Program, Boston University, 24 Cummington Street, Boston, MA 02215, USA

2 Department of Biochemistry and Molecular Pharmacology and Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA

3 Department of Biomedical Engineering, 44 Cummington Street, Boston University, Boston, MA 02215, USA

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Genome Biology 2010, 11:R23 doi:10.1186/gb-2010-11-2-r23

Published: 26 February 2010

Additional files

Additional file 1:

A Word document containing supplementary materials. Background knowledge of genetic buffering effect; comparison between different enrichment approaches; supplementary tables and figures.

Format: DOC Size: 905KB Download file

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Open Data

Additional file 2:

A zip file containing the simulation output files of six test sets.

Format: ZIP Size: 875KB Download file

Open Data