Genome Biology

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Open Access Research

Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells

Thomas K Albert1, Korbinian Grote2, Stefan Boeing1 and Michael Meisterernst1*

Author Affiliations

1 Institute of Molecular Tumor Biology (IMTB), University of Muenster, Robert-Koch-Str. 43, 48149 Muenster, Germany

2 Genomatix Software GmbH, Bayerstr. 85a, 80335 Munich, Germany

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Genome Biology 2010, 11:R33 doi:10.1186/gb-2010-11-3-r33

Published: 15 March 2010

Additional files

Additional file 1:

Aligned core promoter regions of TFIIB target genes. Nucleotide frequency plots of TSS-aligned core promoter regions from high-, low- and no-TFIIB genes.

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Additional file 2:

Data set of TFIIB and NC2 ChIP-chip signals. Log2-scaled ChIP/input ratios of probeset signals from TFIIB and NC2 ChIP-chip experiments using two biological samples (Px5, chromatin from LCL721 B cells of passage 5; Px7, chromatin from LCL721 B cells of passage 7) on a NimbleGen human (HG17) promoter array. The data set includes the median, mean and standard deviation of 24,134 probesets, each composed of 15 individual 50-oligomer probes.

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