Are homologies in vertebrate sex determination due to shared ancestry or to limited options?
1 Research School of Biology, the Australian National University, Canberra, ACT 0200, Australia
2 Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Genome Biology 2010, 11:205 doi:10.1186/gb-2010-11-4-205Published: 30 April 2010
The same candidate genes and the same autosomes are repeatedly used as sex chromosomes in vertebrates. Are these systems identical by descent, or are some genes or chromosomes intrinsically better at triggering the first steps of sex determination?