Research
Small variable segments constitute a major type of diversity of bacterial genomes at the species level
1 INRA, UMR1319, Micalis, Bat 222, Jouy en Josas, 78350, France
2 INSERM U722 and Université Paris 7, Faculté de Médecine, Site Xavier Bichat, Paris, 75018, France
3 CNRS-UMR 8030 & CEA/IG/Genoscope, Laboratoire d'Analyses Bioinformatiques en Génomique et Métabolisme (LABGeM), rue Gaston Crémieux, Evry, 91057, France
4 CEA, Institut de Génomique, Genoscope, rue Gaston Crémieux, Evry, 91057, France
Genome Biology 2010, 11:R45 doi:10.1186/gb-2010-11-4-r45
Published: 30 April 2010Additional files
Additional file 1:
Neighbor joining trees based on genomic MUMi distances of the strains selected for the maximal genomes alignments.
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Additional file 2:
Choice of the maximum divergence level for inclusion of ClustalW aligned sequences into the backbone.
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Additional file 3:
Distribution of the VS sizes in the five-genome alignments.
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Additional file 4:
List of genes containing microdiversity loci in the E. coli five-genome alignments.
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Additional file 5:
List of genes containing microdiversity loci in the E. coli B2 five-genome alignments.
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Additional file 6:
List of genes containing microdiversity loci in the S. aureus five-genome alignments.
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Additional file 7:
List of genes containing microdiversity loci in the S. pyogenes five-genome alignments.
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Additional file 8:
Distribution of the E. coli genes containing microdiversity loci in functional categories.
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Additional file 9:
List of genes placed downstream of microdiversity loci in the E. coli five-genome alignments.
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Additional file 10:
List of genes placed downstream of microdiversity loci in the E. coli B2 five-genome alignments.
Format: XLS Size: 33KB Download file
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Additional file 11:
List of genes placed downstream of microdiversity loci in the S. aureus five-genome alignments.
Format: XLS Size: 71KB Download file
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Additional file 12:
List of genes placed downstream of microdiversity loci in the S. pyogenes five-genome alignments.
Format: XLS Size: 35KB Download file
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Additional file 13:
Distribution of the E. coli genes placed downstream of microdiversity loci in functional categories.
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Additional file 14:
Loci occupancy in the five-genome alignments.
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