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Highly Accessed Review

Between a chicken and a grape: estimating the number of human genes

Mihaela Pertea and Steven L Salzberg*

Author affiliations

Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA

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Citation and License

Genome Biology 2010, 11:206  doi:10.1186/gb-2010-11-5-206

Published: 5 May 2010

Abstract

Many people expected the question 'How many genes in the human genome?' to be resolved with the publication of the genome sequence in 2001, but estimates continue to fluctuate.