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Highly Accessed Review

The origin and early evolution of eukaryotes in the light of phylogenomics

Eugene V Koonin

Author Affiliations

National Center for Biotechnology Information, National Institutes of Health, Bethesda, MD 20894, USA

Genome Biology 2010, 11:209  doi:10.1186/gb-2010-11-5-209

Published: 5 May 2010

Abstract

Phylogenomics of eukaryote supergroups suggest a highly complex last common ancestor of eukaryotes and a key role of mitochondrial endosymbiosis in the origin of eukaryotes.