Table 1

Loci associated with multiple autoimmune diseases

Chromosome

Position

Gene(s)

Disease*

References


1

67466790

IL23R

Psoriasis, CD, UC

[7,12,53]

1

114179091

PTPN22

SLE, CD, RA, T1D

[7,8,54,55]

1

116905738

CD58

MS, RA

[5,11]

1

205006527

IL10

SLE, T1D, UC

[6,8,14]

2

102437000

IL18RAP

T1D, celiac

[9]

2

191672878

STAT4

RA, SLE

[56]

2

204402121

CTLA4

RA, T1D, celiac

[6,13,57]

4

25694609

RBPJ

T1D, RA

[6]

4

123351942

IL2

T1D, Celiac, RA, UC

[6,25,58]

5

150437678

TNIP1

SLE, psoriasis

[8]

5

158650367

IL12B

Psoriasis, CD

[7,12]

6

106541962

PRDM1, ATG5

CD, RA, SLE

[5,7,8]

6

138014761

TNFAIP3

Celiac, RA, SLE, psoriasis

[12,13,59-61]

6

159385965

TAGAP

Celiac, RA

[5,10]

6

167357978

CCR6

CD, RA

[7]

7

128376236

IRF5

SLE, RA

[31,62]

8

11377591

BLK

SLE, RA

[35,63]

10

6138955

IL2RA

RA, MS, T1D

[6,64]

10

6430456

PRKCQ

T1D, RA

[4,65]

16

11074189

CLEC16A

MS, T1D

[11,66]

18

12769947

PTPN2

CD, celiac, T1D

[7,13,66]


*CD, Crohn's disease; MS, multiple sclerosis; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; T1D, type 1 diabetes; UC, ulcerative colitis.

Plenge Genome Biology 2010 11:212   doi:10.1186/gb-2010-11-5-212