Additional file 6.
A figure showing comparison of drug-induced effects in mouse striatum. (a-g) Average activity of time-dependent, drug-induced gene expression patterns. The results are presented as mean changes in gene expression (measured using z-values, in the extended A, B1, B2 and B3 groups of genes). The values are relative to the level of transcript abundance in naïve animals (at each of the time points 1, 2, 4 and 8 h). The thickness of the line is proportional to the number of genes in each cluster. (h,i) Matrices of correlation between all compared drug-induced gene expression profiles. The results were obtained using (h) DNA microarrays and (i) qPCR. The qPCR analysis was used to validate microarray results (Additional file 3).
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Piechota et al. Genome Biology 2010 11:R48 doi:10.1186/gb-2010-11-5-r48