Receiver operating characteristic curve for NBC trained with protein pairs extracted from Reactome pathways as the positive data set, and random pairs as the negative data set. This curve was created using an independent test data set generated from pathways imported from non-Reactome pathway databases. The positions for the cutoff values 0.25, 0.50 and 0.75 are marked from right to left in the inset. The area under the curve (AUC) for this receiver operating characteristic (ROC) curve is 0.93.
Wu et al. Genome Biology 2010 11:R53 doi:10.1186/gb-2010-11-5-r53