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Evidence for natural antisense transcript-mediated inhibition of microRNA function

Mohammad Ali Faghihi1, Ming Zhang34, Jia Huang5, Farzaneh Modarresi1, Marcel P Van der Brug1, Michael A Nalls6, Mark R Cookson6, Georges St-Laurent7 and Claes Wahlestedt12*

Author Affiliations

1 Department of Neuroscience, The Scripps Research Institute, Scripps Florida, 130 Scripps Way, Jupiter, FL 33458, USA

2 Department of Molecular Therapeutics, The Scripps Research Institute, Scripps Florida, 130 Scripps Way, Jupiter, FL 33458, USA

3 T-6, Los Alamos National Laboratory Los Alamos National Laboratory, Los Alamos, NM 87545, USA

4 Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, NM 87545, USA

5 Miami Institute for Human Genomics, Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33101, USA

6 Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, NIH, Bldg 35, 9000 Rockville Pike, Bethesda, MA 20892, USA

7 Department of Biology, Brown University, 244 Thayer Street, Providence, RI 02912, USA

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Genome Biology 2010, 11:R56  doi:10.1186/gb-2010-11-5-r56

Published: 27 May 2010

Additional files

Additional file 1:

an Excel spreadsheet listing conserved sense-antisense pairs, their accession numbers and potential miRNA-binding sites in overlapping and non-overlapping regions.

Format: XLS Size: 453KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data