Dramatic changes in transcription factor binding over evolutionary time
1 Banting and Best Department of Medical Research and Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada
2 Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada
Genome Biology 2010, 11:122 doi:10.1186/gb-2010-11-6-122Published: 1 June 2010
A recent study reveals a surprisingly high degree of change in the occupancy patterns of two transcription factors in the livers of five vertebrates.