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MicroRNA processing without Dicer

Anne Dueck1 and Gunter Meister12*

Author Affiliations

1 Laboratory of RNA Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany

2 Universität Regensburg, Universitätsstrasse 31, 93053 Regensburg, Germany

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Genome Biology 2010, 11:123  doi:10.1186/gb-2010-11-6-123

Published: 21 June 2010

Abstract

The canonical processing of precursor microRNAs requires the endonuclease Dicer. A recent study shows that microRNAs can be processed independently of Dicer but instead require Argonaute 2.