How do proteins gain new domains?

Research highlight

Joseph A Marsh and Sarah A Teichmann^*

MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK

For all author emails, please log on.

Genome Biology 2010, 11:126 doi:10.1186/gb-2010-11-7-126

Published: 15 July 2010

A study of the contributions of different mechanisms of domain gain in animal proteins suggests that gene fusion is likely to be most frequent.