Review
Nuclear transcription factors in mammalian mitochondria
1 Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK
2 University of Cambridge, Department of Oncology, Hutchison/MRC Research Centre, Hills Road, Cambridge, CB2 0XZ, UK
3 Centro Nacional de Investigaciones Cardiovasculares, Melchor Fernandez Almagro 3, 28029 Madrid, Spain
4 Departamento de Bioquímica, Universidad de Zaragoza, Pedro Cerbuna 9, 50009 Zaragoza, Spain
Genome Biology 2010, 11:215 doi:10.1186/gb-2010-11-7-215
Published: 29 July 2010Abstract
Nuclear transcription factors have been detected in mammalian mitochondria and may directly regulate mitochondrial gene expression. Emerging genomics techniques may overcome outstanding challenges in this field.
