Additional file 10.
Figure S7. Model for excess mRNA production per PolII. Before stress, a gene with an overlapping CUT will be associated with PolII molecules producing mRNA (right arrow) as well as PolII molecules producing rapidly degraded 'cryptic' transcripts (left arrows). After stress, repression of the CUT promoter and activation of the ORF promoter will result in a greater proportion of mRNA-producing PolII molecules associated with the ORF. Note that either ORF promoter activation or CUT promoter repression alone would be sufficient to increase the relative proportion of productive PolII relative to overall PolII, but both are shown here to illustrate the point.
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Kim et al. Genome Biology 2010 11:R75 doi:10.1186/gb-2010-11-7-r75