Genome Biology

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The missing graphical user interface for genomics

Michael C Schatz

Genome Biology 2010, 11:128 doi:10.1186/gb-2010-11-8-128

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CloVR: A virtual machine for automated and portable sequence analysis from the desktop using cloud computing

Samuel V Angiuoli, Malcolm Matalka, Aaron Gussman, Kevin Galens, Mahesh Vangala, David R Riley, Cesar Arze, James R White, Owen White, W Florian Fricke BMC Bioinformatics 2011, 12:356 (30 August 2011)

Cloud Virtual Resource (CloVR) is a new desktop application for large-scale sequence analysis using remote computing resources that provides several automated pipelines for microbial genomics, including 16S, whole genome and metagenome sequence analysis.

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Microarrays, deep sequencing and the true measure of the transcriptome

John H Malone, Brian Oliver BMC Biology 2011, 9:34 (31 May 2011)

Global measures of gene expression can now be extracted either from microarrays or from RNA-seq, which do not always seem to give the same answer. Malone and Oliver review the advantages and limitations of each and conclude that, with some important exceptions, they tell the same story.