Genome Biology

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Cloud-scale RNA-sequencing differential expression analysis with Myrna

Ben Langmead, Kasper D Hansen and Jeffrey T Leek*

Genome Biology 2010, 11:R83 doi:10.1186/gb-2010-11-8-r83

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CloVR: A virtual machine for automated and portable sequence analysis from the desktop using cloud computing

Samuel V Angiuoli, Malcolm Matalka, Aaron Gussman, Kevin Galens, Mahesh Vangala, David R Riley, Cesar Arze, James R White, Owen White, W Florian Fricke BMC Bioinformatics 2011, 12:356 (30 August 2011)

Cloud Virtual Resource (CloVR) is a new desktop application for large-scale sequence analysis using remote computing resources that provides several automated pipelines for microbial genomics, including 16S, whole genome and metagenome sequence analysis.

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The real cost of sequencing: higher than you think!

Andrea Sboner, Xinmeng Mu, Dov Greenbaum, Raymond K Auerbach, Mark B Gerstein Genome Biology 2011, 12:125 (25 August 2011)

The sharp decrease in the cost of 'data generation' has not been matched by a comparable decrease in the cost of the computational infrastructure required to mine the data

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rnaSeqMap: a Bioconductor package for RNA sequencing data exploration

Anna Leśniewska, Michał J Okoniewski BMC Bioinformatics 2011, 12:200 (25 May 2011)

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An overview of the Hadoop/MapReduce/HBase framework and its current applications in bioinformatics

Ronald C Taylor BMC Bioinformatics 2010, 11(Suppl 12):S1 (21 December 2010)