Software
Cloud-scale RNA-sequencing differential expression analysis with Myrna
Author affiliations
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Citation and License
Genome Biology 2010, 11:R83 doi:10.1186/gb-2010-11-8-r83
Published: 11 August 2010Abstract
As sequencing throughput approaches dozens of gigabases per day, there is a growing need for efficient software for analysis of transcriptome sequencing (RNA-Seq) data. Myrna is a cloud-computing pipeline for calculating differential gene expression in large RNA-Seq datasets. We apply Myrna to the analysis of publicly available data sets and assess the goodness of fit of standard statistical models. Myrna is available from http://bowtie-bio.sf.net/myrna webcite.
