Genome Biology

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Intronic motif pairs cooperate across exons to promote pre-mRNA splicing

Shengdong Ke and Lawrence A Chasin*

Author Affiliations

Department of Biological Sciences, Columbia University, 1212 Amsterdam Ave, MC 2433, New York, NY 10027, USA

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Genome Biology 2010, 11:R84 doi:10.1186/gb-2010-11-8-r84

Published: 12 August 2010

Additional files

Additional file 1:

Figures S1, S2, and S3, and Tables S1 and S3. Figure S1: distribution of pentamer pairs around constitutive exons. Figure S2: scheme for grouping exons according to the GC content of their flanks. Figure S3: tissue-specific expression of six hnRNPs. Table S1: results with no GC balancing. Table S3: overlap of UpDp downstream motifs with other reported intronic motif sets.

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Additional file 2:

Table S2. List of co-occurring pairs.

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Additional file 3:

Table S4. Tissue-specific expression of genes with co-occurring motif pairs.

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