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Unmasking a role for sex chromosomes in gene silencing

Danielle M Maatouk and Blanche Capel*

Author Affiliations

Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA

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Genome Biology 2010, 11:134  doi:10.1186/gb-2010-11-9-134

Published: 27 September 2010

Abstract

Several sexually dimorphic phenotypes correlate with sex-chromosome dosage rather than with phenotypic sex. New research suggests that sex chromosome dimorphism helps to regulate gene silencing.