Figure 4.

Relationship between protein stability and mRNA expression. The experimentally measured stability data were obtained from the ProTherm database [54], and the expression data for E. coli were obtained from the study by Lu et al. [78]. (a) Correlation between mRNA expression and melting temperature for 28 proteins (r = -0.14, P = 0.45). (b) Correlation between mRNA expression and folding free energy for 23 proteins (r = -0.08, P = 0.70). The dashed red line represents the linear regression between each variable and the natural logarithm of the expression values.