Exclusive expression of the exons of the 3' partner genes taking part in the fusions. Exonic expression of CEP250 in ZMYND8-CEP250 (upper), ENSG00000236127 in CSE1L-ENSG00000236127 (second from top), GSDMB in TATDN1-GSDMB (second from bottom) and BCAS4 in BCAS3-BCAS4 (lower) is indicated by sequencing coverage (red). Copy number changes measured by aCGH (black dots) in reference to normal copy number (horizontal grey line) and fusion break points (vertical grey line) are indicated. Chromosomal positions and transcript structures are shown below the aCGH data. Transcript structures above and below chromosome coordinates denote forward and reverse strand, respectively.
Edgren et al. Genome Biology 2011 12:R6 doi:10.1186/gb-2011-12-1-r6