Table 2

Putative PKS and NRPS genes of A. benhamiae, T. verrucosum, and C. immitis

Type

LocusLink Arthroderma benhamiae

LocusLink Trichophyton verrucosum

LocusLink Coccidioides immitis

Domain architecture

PKSs

Non-reducing

ARB_00538

TRV_00386

-

KS-AT-ACP

ARB_03291

TRV_02519

CIMG_13102

KS-AT-ACP-ME^a

-

-

CIMG_05571

KS-AT-ACP

-

-

CIMG_04689

KS-AT-ACP-ME

-

-

CIMG_03162

KS-AT-ACP

ARB_07994

TRV_04611

CIMG_08569

KS-AT-ACP-ACP-TE

-

-

CIMG_08564

AT-KS-ACP-TE

Reducing

ARB_01525

TRV_04236

CIMG_13632

KS-AT-ME-ER-KR-ACP

ARB_05854

TRV_06867

-

KS-AT-KR-ACP^b

ARB_06393

TRV_01071

-

KS-AT-ME-ER-KR-ACP

ARB_05333

TRV_06912

CIMG_02398

KS-AT-DH-MT-ER-KR-ACP

ARB_07933

TRV_04104

-

KS-AT-ME-ER-KR-ACP

ARB_07966

TRV_04285

-

KS-AT-ME-KR-ACP

-

-

CIMG_05569

KS-AT-DH-ER-KR-ACP

-

-

CIMG_03014

KS-AT-DH-ER-KR-ACP

ARB_00195

TRV_05651

CIMG_07298

A-T-C-T-C

-

-

CIMG_01429

A-T-C-T

ARB_01698

TRV_01735

CIMG_09750

C-A-T-C-A-T-C-A-T-C-A-T-C-A-T-C-T-C-T

ARB_02149

-

-

C-A-T-C-A-T-C-A-T-C-A-T-C^c

ARB_02226

TRV_00553

-

A-T-C-A-T-C-A-T-C

ARB_02570

TRV_5508

-

A-T-C

ARB_02750

TRV_06186

-

A-T-C-A-T-C-A-T-C-A-T-C-A-T-C-T

ARB_03095

TRV_06056

-

T-C-A-T-C/T-C-A

NRPSs

ARB_03768

TRV_07570

-

A-C-A-T-C-A-T

ARB_04984

TRV_06313

CIMG_01861

A-T-C-A-T-C

ARB_05131

TRV_07837

-

A-T-C-A-T-C-A-T

ARB_05579

TRV_06828

-

T-C-A-T-C-A-T

ARB_06786

TRV_05681

-

A-T-C

ARB_07686

TRV_05452

CIMG_00941

A-T-C-A-T-C-T-C-A-T-C-T-C-T-C

ARB_07850

TRV_01776

-

A-T-C/A-T-C-A-T

ARB_07862

TRV_04720

-

A-T-C-A-T-C-T

ARB_07534

TRV_00508

-

KS-AT-DH-ER-KR-ACP-C-A-T

PKS/NRPS hybrids

ARB_02973

TRV_03721

CIMG_06629

KS-AT-ME-KR-ACP-C-A-T

ARB_07844

TRV_05146

-

A-T-KS-AT-KR-ACP-TE

^aPotential citrinin-like product; similar to pksCT BAD44749.1. ^bProduct 6-methyl-salicylic acid; similar to 6-MSA synthase CAA39295.1. ^cUnique for A. benhamiae. A, adenylation domain; ACP(PP), acyl carrier protein, or phosphopantetheine domain; AT, acetyltransferase domain; C, condensation domain; DH, dehydratase domain; E, epimerization domain; ER, enoyl reductase domain; KR, ketoacyl reductase domain; KS, beta-ketoacyl synthase domain; ME, methyltransferase domain; T, thiolation domain; TE, thioesterase domain.

Burmester et al. Genome Biology 2011 12:R7   doi:10.1186/gb-2011-12-1-r7