Revealing the molecular signatures of host-pathogen interactions
1 Infectious Diseases, Genome Institute of Singapore, 60 Biopolis Street, #02-01 Genome Building, Singapore 138672
2 NUS-GIS Centre for Molecular Epidemiology, 60 Biopolis Street, #02-01 Genome Building, Singapore 138672
3 Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, Level 12, 1E Kent Ridge Road, Singapore 119228
4 Department of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University of Singapore, 16 Medical Drive (MD 3), Singapore 117597
Genome Biology 2011, 12:229 doi:10.1186/gb-2011-12-10-229Published: 19 October 2011
Advances in sequencing technology and genome-wide association studies are now revealing the complex interactions between hosts and pathogen through genomic variation signatures, which arise from evolutionary co-existence.