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Highly Accessed Review

Revealing the molecular signatures of host-pathogen interactions

Chiea-Chuen Khor123 and Martin L Hibberd14*

Author affiliations

1 Infectious Diseases, Genome Institute of Singapore, 60 Biopolis Street, #02-01 Genome Building, Singapore 138672

2 NUS-GIS Centre for Molecular Epidemiology, 60 Biopolis Street, #02-01 Genome Building, Singapore 138672

3 Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, Level 12, 1E Kent Ridge Road, Singapore 119228

4 Department of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University of Singapore, 16 Medical Drive (MD 3), Singapore 117597

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Citation and License

Genome Biology 2011, 12:229  doi:10.1186/gb-2011-12-10-229

Published: 19 October 2011

Abstract

Advances in sequencing technology and genome-wide association studies are now revealing the complex interactions between hosts and pathogen through genomic variation signatures, which arise from evolutionary co-existence.