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Highly Accessed Review

Bacterial epidemiology and biology - lessons from genome sequencing

Julian Parkhill1 and Brendan W Wren2*

Author Affiliations

1 The Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK

2 Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK

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Genome Biology 2011, 12:230  doi:10.1186/gb-2011-12-10-230

Published: 24 October 2011

Abstract

Next-generation sequencing has ushered in a new era of microbial genomics, enabling the detailed historical and geographical tracing of bacteria. This is helping to shape our understanding of bacterial evolution.