Table 1

Detection of depleted hairpins in reference depletion screens

Un-filtered

Filtered


Depletion

Min FPR

FNR

Min FPR

FNR


25%

0.00%

50.05%

0.00%

49.95%

50%

0.00%

4.21%

0.00%

2.89%

75%

0.00%

0.74%

0.00%

0.00%


The false positive and false negative rates at a range of log ratio thresholds were calculated by comparing each depletion group to the non-depleted hairpins. This was repeated for all hairpins and after filtering to exclude hairpins with low representation (<100 raw reads) in the reference set. The minimum false positive rate (Min FPR) found is shown along with the associated false negative rate (FNR).

Sims et al. Genome Biology 2011 12:R104   doi:10.1186/gb-2011-12-10-r104

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